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Home :: Skin Disorders :: Lyme Disease Lyme Disease Information - Symptoms (With Pictures) & TreatmentIn 1975 Lyme disease got its name when two mothers, in Lyme & East Haddam Connecticut, contacted the health department because they were alarmed at the many cases of arthritis in children in their area. "Lyme arthritis" as it was named by researchers from Yale was discovered in 39 children & 12 adults. This same illness, although not formally named until 1975, was observed in the 1800s. In 1981 the bacteria which passes the disease via the bite of a tick was isolated by Willy Burgdorfer at the Rocky Mountain Laboratories. It was named "Borrelia burgdorfere" (Bb) after the man who discovered it. A multisystemic disorder, Lyme disease is caused by the spirochete, Borrelia burgdorferi, which is carried by the minute tick Ixodes dammini or another tick in the Ixodidae family. It often begins in the summer with the classic skin lesion called erythematic chronicum migrans (ECM). Weeks or months later, cardiac or neurologic abnormalities sometimes develop, possibly followed by arthritis Initially, Lyme disease was identified in a group of children in Lyme, Connecticut. Now Lyme disease is known to occur primarily in three parts of the United States:
Although Lyme disease is endemic to these areas, cases have been reported in 43 states & 20 other countries, including Germany, Switzerland, France, & Australia.
Signs & symptoms of Lyme disease
Stage 1 :- ECM heralds stage I with a red macule or papule, often at the site of a tick bite. This lesion often feels hot & itchy & may grow to more than 20" (50 cm) in diameter. Within a few days, more lesions may erupt along with a malar rash, conjunctivitis, or diffuse urticaria. In 3 to 4 weeks, lesions are replaced by small red blotches, which persist for several more weeks. Malaise & fatigue are constant, but other findings are intermittent: headache, fever, chills, achiness, & regional lymphadenopathy. Less common effects are meningeal irritation, mild encephalopathy, migrating musculoskeletal pain, & hepatitis. A persistent sore throat & dry cough may appear several days before ECM. Stage 2 :- Weeks to months later, the second stage begins with neurologic abnormalities - fluctuating meningoencephalitis with peripheral & cranial neuropathy - that usually resolve after days or months. Facial palsy is especially noticeable. Cardiac abnormalities, such as a brief, fluctuating atrioventricular heart block, may also develop Stage 3 :- Characterized by arthritis, stage 3 begins weeks or years later. Migrating musculoskeletal pain leads to frank arthritis with marked swelling, especially in the large joints. Recurrent attacks may precede chronic arthritis with severe cartilage & bone erosion. DiagnosisBecause isolation of B. burgdorferi is unusual in humans & because indirect immunofluorescent antibody tests are marginally sensitive, diagnosis often rests on the characteristic ECM lesion & related clinical findings, especially in endemic areas. Mild anemia & an elevated erythrocyte sedimentation rate, leukocyte count, serum immunoglobulin M level, & aspartate aminotransferase level support the diagnosis. Treatment of Lyme diseaseA 10- to 20-day course of oral tetracycline is the treatment of choice for adults. Penicillin & erythromycin are alternates. Oral penicillin is usually prescribed for children. When given in the early stages, these drugs can minimize later complications. When given during the late stages, high-dose penicillin LV. may be a successful treatment. There is now a vaccine (Lymerix) available to prevent Lyme disease. For maximal effectiveness, it's given as a series of three injections. CLINICAL TIP Neurologic abnormalities are best treated with LV. ceftriaxone or LV. penicillin. There is no specific home treatment for children with Lyme disease. Make sure your child takes the required medication as prescribed by your child's doctor, & take steps to prevent & control Lyme disease. prohibition of Lyme disease
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