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erythematic Nodosum (Pictures)

erythematic nodosum is an important acute inflammatory/immunologic reaction pattern of the panniculus characterized by the appearance of painful nodules on the lower legs & caused by multiple & diverse etiologies. The nodules may occur anywhere there is fat under the skin, including the thighs, arms, trunk, face, & neck.

The age of onset is from 15 to 30 years, but age distribution is related to etiology. erythematic nodosum is three times more common in females than in males. Etiologic associations include infections, drugs, & other inflammatory/granulomatous diseases, notably sarcoidosis.

reason of erythematic Nodosum

There are many reason of erythematic nodosum. The most common cause of erythematic nodosum is medications, especially sulfa drugs & some brands of the oral contraceptive pill. If the pill is changed, the erythematic nodosum resolves. Apart from drugs, infections are the largest cause of erythematic nodosum, including 'Strep" throat, TB & others.

Signs & symptoms of erythematic Nodosum

The following are the most common symptoms of erythematic nodosum. However, each individual may experience symptoms differently:

• raised bruises on shins
• fever
• joint pain
• enlarged lymph nodes in chest

Young adults are particularly susceptible to erythematic nodosum

Diagnosis

Diagnosis rests on clinical criteria, may be supported by histopathology. A biopsy (removal of tissue for examination under a microscope) of a bump can usually confirm the diagnosis. However, the exact cause can not always be identified.

Treatment of erythematic Nodosum

• The most effective treatment is to remove the cause. Sometimes no cause is found, & complete resolution takes four to six weeks.
• An aspirin like drug called Indocin often improves the condition. This medication should be taken three times a day with food or Maalox.
• A course of potassium iodide is often effective in clearing it.
• Anti-inflammatory Treatment Salicylates, NSAIDs.

prohibition of erythematic Nodosum

• Bed rest is advised for severe EN.
• Firm supportive bandages or stockings should be worn.
• Topical therapy is not generally needed, although hot or cold compresses may reduce discomfort.